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GLP-1 MEDICAL WEIGHT CARE

Direct answer: how Mounjaro is positioned in Japan

In Japan, Mounjaro (tirzepatide) is approved for type 2 diabetes. Use for weight management is off-label and requires individual medical assessment, risk explanation, and a prescribing decision. Dose is based on medical history, prior use, response, adverse effects, and concomitant medicines.

Primary source: PMDA prescribing information

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Once-weekly injection / dual GIP and GLP-1 receptor agonist

Mounjaro Online Consultation Hub: 2.5mg, 5mg, 7.5mg, 10mg, 12.5mg and 15mg

A comprehensive English hub for Mounjaro (tirzepatide) 2.5mg, 5mg, 7.5mg, 10mg, 12.5mg and 15mg, covering dose positioning, prices, side effects, online consultation, pharmacy counseling, delivery and detailed related articles.

In Japan, Mounjaro is approved for type 2 diabetes. Use for weight management in private care is off-label.

Key points first

2.5mg–15mg

Escalation is not automatic. If the current dose is effective and tolerated, it may be continued.

2026-09-23

In Japan, Mounjaro is approved for type 2 diabetes. Use for weight management in private care is off-label.

How the 2.5mg-to-15mg dose pathway is considered

2.5mg

Common starting dose used to assess tolerability.

5mg

Usual maintenance dose considered after four weeks at 2.5mg.

7.5mg

Intermediate step considered after at least four weeks when 5mg is insufficient.

10mg

Higher dose considered when 7.5mg remains insufficient and tolerability is acceptable.

12.5mg

May be considered when 10mg remains insufficient and tolerability is acceptable.

15mg

The maximum dose, considered cautiously when 12.5mg remains insufficient and tolerability is acceptable.

Escalation is not automatic. If the current dose is effective and tolerated, it may be continued.

Price table

Dose 1 month 3 months 6 months
2.5mg ¥11,800 ¥31,800 ¥61,800
5mg ¥18,800 ¥51,800 ¥99,800
7.5mg ¥29,800 ¥79,800 ¥144,800
10mg ¥37,800 ¥97,800 ¥179,800
12.5mg ¥46,800 ¥124,800 ¥239,800
15mg ¥54,800 ¥146,800 ¥279,800
View all prices Ask about online consultation

How to interpret clinical-trial evidence for 10mg

SURMOUNT-1 was a 72-week trial in adults with obesity or overweight without diabetes. Mean body-weight change in the 10mg group was −19.5%. This was a controlled trial with defined participants, lifestyle intervention and follow-up, and it does not predict an individual result.

SURMOUNT-1 dose-group weight change chart

The chart visualizes group means reported in the paper. It does not predict an individual response at each dose.

The SURPASS program also evaluated tirzepatide doses including 10mg in people with type 2 diabetes. Obesity and diabetes trials have different populations and objectives, so their results should not be treated as interchangeable.

Safety and adverse effects

Common adverse effects include nausea, vomiting, diarrhea, constipation, abdominal discomfort and reduced appetite. Gastrointestinal events are reported more often during dose escalation.

Seek prompt medical care for persistent severe abdominal pain, repeated vomiting, marked dehydration, jaundice or altered consciousness.

From consultation to delivery

  1. Complete an online medical consultation
  2. If prescribed, information is sent to a partner pharmacy
  3. The pharmacy contacts you to arrange medication counseling
  4. Complete online counseling and pay the pharmacy
  5. Collect the medicine or receive delivery within Japan

Why does AURELIA ONLINE use this pricing and payment structure?

AURELIA ONLINE uses an outside-pharmacy model. The medical consultation and prescribing decision are handled by Chiaro Clinic, while dispensing and pharmacist counselling are handled by a partner pharmacy. For that reason, payment can be split between the clinic and the pharmacy. To make comparison easier, the public price table shows the combined tax-included total. It is not an automatic subscription; dose and continuation are reviewed at each consultation.

Common questions across all Mounjaro doses

2.5 mg — starting dose

Usually used to start treatment and assess gastrointestinal tolerability before moving to 5 mg.

When to move from 2.5 mg to 5 mg

5 mg — usual maintenance dose

If response is adequate, there is no requirement to move higher simply because higher strengths exist.

When to consider 7.5 mg

7.5 mg — escalation step

Considered after adequate time on 5 mg when response remains insufficient and tolerability is acceptable.

7.5 mg to 10 mg

10–15 mg — higher-dose options

Higher doses are not a goal in themselves. Dose choice should balance benefit, adverse effects, weight and glucose control.

New: Mounjaro 12.5 mg & 15 mg High-Dose Guides

A complete high-dose cluster covering escalation, side effects, plateau, long-term maintenance, dose reduction and prices in Japan.

The goal is not to reach the maximum dose; it is to use the dose that best balances benefit, tolerability and long-term safety.

Mounjaro guides and articles

Restarting Mounjaro

Why restart dose depends on the treatment gap, previous dose and adverse effects.

How do I receive the medication?

After prescribing, the partner pharmacy provides counselling and payment instructions, followed by delivery or the agreed pickup method.

Does the displayed price include the consultation fee?

The current public price is shown as a combined tax-included total of consultation and medication. Delivery fees may be separate.

Why can payment be split between the clinic and pharmacy?

Because the clinic provides the medical consultation/prescribing decision and the partner pharmacy provides dispensing and pharmacist counselling. The website shows the combined total for clarity.

What if my weight plateaus?

A short plateau does not automatically mean treatment failure. Review bowel habits, food intake, activity, treatment duration and the overall amount already lost.

Can I lose muscle?

Large weight loss can include some lean mass. Adequate nutrition, protein and resistance exercise are important when appropriate.

What about pregnancy or trying to conceive?

Mounjaro should not be used during pregnancy. Discuss planned pregnancy with the prescribing doctor in advance.

Does injection site change how much weight I lose?

No specific approved injection site is expected to produce greater weight loss. Correct technique and site rotation matter.

Can everyone use 12.5 mg or 15 mg?

No. These are higher-dose options reached stepwise when medically appropriate. 15 mg is the maximum weekly dose.

When is 7.5 mg or 10 mg considered?

After adequate time at the preceding dose when response is insufficient and adverse effects are acceptable.

Do I have to move from 5 mg to 7.5 mg?

No. If 5 mg is working well, escalation may not be necessary.

What is 2.5 mg for?

It is the usual starting dose. The first weeks are used to assess tolerability before the standard move to 5 mg.

Is this a subscription?

No. Treatment continuation and dose are reviewed at each consultation.

Frequently asked questions

References and official information

  1. PMDA: Mounjaro prescribing information and product information
  2. Jastreboff AM, et al. Tirzepatide Once Weekly for the Treatment of Obesity. NEJM. 2022.
  3. Frías JP, et al. Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes. NEJM. 2021.
  4. FDA Mounjaro prescribing information.
Editorial and medical review
Edited by: AURELIA ONLINE Editorial Team
Medical information reviewed by: Chiaro Clinic (reviewed August 30, 2026)
Editorial and corrections policy · Legal and medical advertising information

In Japan, Mounjaro is approved for type 2 diabetes. Use for weight management is off-label. Individual diagnosis and prescribing decisions require a medical consultation.